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Journal article

Macroevolution of complex retroviruses.

Abstract:

Retroviruses can leave a "fossil record" in their hosts' genomes in the form of endogenous retroviruses. Foamy viruses, complex retroviruses that infect mammals, have been notably absent from this record. We have found an endogenous foamy virus within the genomes of sloths and show that foamy viruses were infecting mammals more than 100 million years ago and codiverged with their hosts across an entire geological era. Our analysis highlights the role of evolutionary constraint in maintaining ...

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Publication status:
Published

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Publisher copy:
10.1126/science.1174149

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
Journal:
Science (New York, N.Y.)
Volume:
325
Issue:
5947
Pages:
1512
Publication date:
2009-09-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:ad309d52-5fbb-4b88-8ac0-2a3ce2167de7
Source identifiers:
209717
Local pid:
pubs:209717

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