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Enantiopure oxazolidinones as chiral acids in the asymmetric protonation of N-Boc pyrrole derived enolates.

Abstract:
The first use of geminally disubstituted oxazolidinones as chiral protonating agents is described: these new acids are able to directly protonate an enolate generated by the ammonia free partial reduction of an electron deficient pyrrole and give up to 68% ee in the pyrroline product.
Publication status:
Published

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Publisher copy:
10.1039/b316719d

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Chemical Communications More from this journal
Volume:
10
Issue:
6
Pages:
722-723
Publication date:
2004-03-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345


Language:
English
Pubs id:
pubs:32653
UUID:
uuid:ad0836d0-6097-4240-a649-18f5b1a484af
Local pid:
pubs:32653
Source identifiers:
32653
Deposit date:
2012-12-19

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