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Journal article

Autoimmune neurological diseases

Abstract:

Myasthenia gravis (MG) is one of the best understood autoantibody-mediated disorders. The pathogenic antibodies against the acetylcholine receptor (AChR) have been well characterized and are known to impair neuromuscular transmission by direct blockade, complement-mediated damage and accelerated receptor-mediated endocytosis. The clinical presentation is characterized by fatigable weakness, with a predilection for the extra-ocular, facial, bulbar, respiratory and proximal limb muscles. Diagno...

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Publisher copy:
10.1016/j.mpmed.2012.07.002

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Medicine (United Kingdom)
Volume:
40
Issue:
10
Pages:
553-557
Publication date:
2012-10-01
DOI:
EISSN:
1365-4357
ISSN:
1357-3039
Source identifiers:
352915
Language:
English
Keywords:
Pubs id:
pubs:352915
UUID:
uuid:ac96dcbd-4aff-4d12-8640-743d806804b4
Local pid:
pubs:352915
Deposit date:
2012-12-19

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