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Hepatitis B Core-Related Antigen Point-of-Care Tests as a Risk Stratification Tool for Treatment Eligibility: Experience From Kenya

Abstract:
We undertook a point-of-care test for hepatitis B core-related antigen in adults with hepatitis B virus in Kilifi, Kenya. A positive test identified all individuals with a hepatitis B viral load >200 000 IU/mL and who were hepatitis B e antigen positive. It also correlated with a higher alanine aminotransferase (ALT) level (P = .03), raised aspartate transaminase-to-platelet ratio index (APRI) (P < .001), and higher elastography scores (P = .03).
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/ofid/ofaf125

Authors


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Institution:
University of Oxford
Role:
Author
ORCID:
0000-0002-6088-4704
More by this author
Role:
Author
ORCID:
0000-0002-1799-8503


Publisher:
Oxford University Press
Journal:
Open Forum Infectious Diseases More from this journal
Volume:
12
Issue:
3
Article number:
ofaf125
Publication date:
2025-03-06
Acceptance date:
2025-03-03
DOI:
EISSN:
2328-8957
ISSN:
2328-8957


Language:
English
Keywords:
Pubs id:
2094542
Local pid:
pubs:2094542
Source identifiers:
2786864
Deposit date:
2025-03-20
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