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Journal article

Single-dose tafenoquine to prevent relapse of Plasmodium vivax malaria

Abstract:

Background Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed “radical cure”). Tafenoquine is a single-dose 8-aminoquinoline that has recently been registered for the radical cure of P. vivax.

Methods This multicenter, double-blind, double-dummy, parallel group, randomized, placebo-controlled trial was conducted in ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0002-7567-5534
Publisher:
Massachusetts Medical Society
Journal:
New England Journal of Medicine More from this journal
Volume:
380
Issue:
3
Pages:
215-228
Publication date:
2019-01-17
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
Pmid:
30650322
Language:
English
Keywords:
Pubs id:
966012
Local pid:
pubs:966012
Deposit date:
2020-06-12

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