Journal article
Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta-analysis
- Abstract:
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OBJECTIVES:
Estimates of depression prevalence in pregnancy and postpartum are based on the Edinburgh Postnatal Depression Scale (EPDS) more than on any other method. We aimed to determine if any EPDS cutoff can accurately and consistently estimate depression prevalence in individual studies.
METHODS:
We analyzed datasets that compared EPDS scores to Structured Clinical Interview for DSM (SCID) major depression status. Random-effects meta-analysis was used to compare prevalence with EPDS cutoffs versus the SCID.
RESULTS:
Seven thousand three hundred and fifteen participants (1017 SCID major depression) from 29 primary studies were included. For EPDS cutoffs used to estimate prevalence in recent studies (≥9 to ≥14), pooled prevalence estimates ranged from 27.8% (95% CI: 22.0%-34.5%) for EPDS ≥ 9 to 9.0% (95% CI: 6.8%-11.9%) for EPDS ≥ 14; pooled SCID major depression prevalence was 9.0% (95% CI: 6.5%-12.3%). EPDS ≥14 provided pooled prevalence closest to SCID-based prevalence but differed from SCID prevalence in individual studies by a mean absolute difference of 5.1% (95% prediction interval: -13.7%, 12.3%).
CONCLUSION:
EPDS ≥14 approximated SCID-based prevalence overall, but considerable heterogeneity in individual studies is a barrier to using it for prevalence estimation.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, 712.0KB, Terms of use)
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- Publisher copy:
- 10.1002/mpr.1860
Authors
- Publisher:
- Wiley
- Journal:
- International Journal of Methods in Psychiatric Research More from this journal
- Volume:
- 30
- Issue:
- 1
- Article number:
- e1860
- Publication date:
- 2020-10-22
- Acceptance date:
- 2020-10-13
- DOI:
- EISSN:
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1557-0657
- ISSN:
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1049-8931
- Pmid:
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33089942
- Language:
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English
- Keywords:
- Pubs id:
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1139417
- Local pid:
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pubs:1139417
- Deposit date:
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2020-11-04
Terms of use
- Copyright holder:
- Lyubenova et al.
- Copyright date:
- 2020
- Rights statement:
- ©2020 The Authors. International Journal of Methods in Psychiatric Research published by John Wiley & Sons Ltd.
- Notes:
- This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, pro-vided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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