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Journal article

Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo.

Abstract:

Understanding the mechanisms that coordinate the orientation of cell division planes during embryogenesis and morphogenesis is a fundamental problem in developmental biology. Here we show that the orphan receptor lat-1, a homolog of vertebrate latrophilins, plays an essential role in the establishment of tissue polarity in the C. elegans embryo. We provide evidence that lat-1 is required for the alignment of cell division planes to the anterior-posterior axis and acts in parallel to known pol...

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Publication status:
Published

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Authors


Langenhan, T More by this author
Prömel, S More by this author
Esmaeili, B More by this author
Waller-Evans, H More by this author
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Journal:
Developmental cell
Volume:
17
Issue:
4
Pages:
494-504
Publication date:
2009-10-05
DOI:
EISSN:
1878-1551
ISSN:
1534-5807
URN:
uuid:ac37ce10-5b78-4679-986c-bb655985b046
Source identifiers:
101118
Local pid:
pubs:101118

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