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The mesocortical dopamine projection to anterior cingulate cortex plays no role in guiding effort-related decisions.

Abstract:

Both mesolimbic dopamine (DA) and the anterior cingulate cortex (ACC) have been implicated in enabling animals to expend effort to obtain greater reward. To investigate the role of the DA pathway to ACC in working for reward, the authors tested rats on a cost-benefit T-maze paradigm in which they could either climb a barrier to obtain large reward in 1 arm (high reward [HR]) or select the low-effort alternative containing less reward (low reward [LR]). Surprisingly, ACC DA depletions had no e...

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Publication status:
Published

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Publisher copy:
10.1037/0735-7044.119.1.323

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Behavioral neuroscience
Volume:
119
Issue:
1
Pages:
323-328
Publication date:
2005-02-05
DOI:
EISSN:
1939-0084
ISSN:
0735-7044
URN:
uuid:abf365fb-0fce-42ad-b0f2-4f098419b53f
Source identifiers:
30293
Local pid:
pubs:30293

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