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The emergence of azithromycin-resistant Salmonella Typhi in Nepal

Abstract:

Background Typhoid fever remains a significant cause of morbidity and mortality in Asia and Africa. The emergence of azithromycin resistance in South Asia is concerning, as azithromycin is one of the last effective oral drugs for treating typhoid. Objectives To describe the molecular mechanism and phylogenetics of azithromycin-resistant (AzithR) Salmonella Typhi isolates from Patan Hospital, Kathmandu, Nepal. Methods Whole-genome sequences of three AzithR S. Typhi isolates (MIC >256 mg/L) ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/jacamr/dlaa109

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Publisher:
Oxford University Press Publisher's website
Journal:
JAC-Antimicrobial Resistanceop Journal website
Volume:
2
Issue:
4
Article number:
dlaa109
Publication date:
2020-12-21
Acceptance date:
2020-11-10
DOI:
EISSN:
2632-1823
Pmid:
34223059
Language:
English
Keywords:
Pubs id:
1185370
Local pid:
pubs:1185370
Deposit date:
2021-07-15

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