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Intracellular antibody capture (IAC) methods for single domain antibodies.

Abstract:

Intracellular single domain antibodies are recombinant proteins, comprising one variable region domain fragment, that bind specifically to intracellular molecules and can interfere with their particular functions within various cellular compartments. They are valuable tools in bioscience and potential macrodrugs in biotherapeutics; however, their application is still limited because of the difficulty and inefficiency of acquisition of functional intracellular antibodies. We describe here the ...

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Volume:
911
Pages:
151-173
Publication date:
2012-01-01
DOI:
ISBN:
9781617799679
Keywords:
Pubs id:
pubs:353641
UUID:
uuid:abc910f2-04c5-4ffc-99bf-caf3705da835
Local pid:
pubs:353641
Source identifiers:
353641
Deposit date:
2013-11-16

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