Journal article
A novel oxygen-sensitive potassium current in rat carotid body type I cells.
- Abstract:
-
1. Hypoxic stimuli depolarize carotid body type I cells causing voltage-gated calcium influx. This study investigates the cause of this membrane depolarization. Isolated type I cells from neonatal (11-16 day) rat carotid bodies were used in the experiments. 2. Tetraethylammonium (TEA; 10 mM), 1 and 5 mM 4-aminopyridine (4-AP) and 20 nM charybdotoxin all failed to evoke a significant rise in [Ca2+]i. Similarly, in perforated patch whole-cell recordings, a combination of 10 mM TEA and 5 mM 4-AP...
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- Publication status:
- Published
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- Publisher copy:
- 10.1113/jphysiol.1997.sp021890
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Authors
Bibliographic Details
- Journal:
- Journal of physiology
- Volume:
- 498 ( Pt 3)
- Issue:
- 3
- Pages:
- 649-662
- Publication date:
- 1997-02-01
- DOI:
- EISSN:
-
1469-7793
- ISSN:
-
0022-3751
- Source identifiers:
-
312280
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:312280
- UUID:
-
uuid:abbc77f1-0f30-4aee-99c3-b49df5bab8c2
- Local pid:
- pubs:312280
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 1997
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