Journal article
MicroRNAs: new players in IBD
- Abstract:
- MicroRNAs (miRNAs) are small non-coding RNAs, 18–23 nucleotides long, which act as post-transcriptional regulators of gene expression. miRNAs are strongly implicated in the pathogenesis of many common diseases, including IBDs. This review aims to outline the history, biogenesis and regulation of miRNAs. The role of miRNAs in the development and regulation of the innate and adaptive immune system is discussed, with a particular focus on mechanisms pertinent to IBD and the potential translational applications.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 4.0MB, Terms of use)
-
- Publisher copy:
- 10.1136/gutjnl-2014-307891
Authors
- Publisher:
- BMJ Publishing Group
- Journal:
- Gut More from this journal
- Volume:
- 64
- Issue:
- 3
- Pages:
- 504-517
- Publication date:
- 2014-12-04
- Acceptance date:
- 2014-10-23
- DOI:
- EISSN:
-
1468-3288
- ISSN:
-
0017-5749
- Pmid:
-
25475103
- Language:
-
English
- Keywords:
- Pubs id:
-
pubs:827881
- UUID:
-
uuid:ab838996-d60f-4dff-a3ae-78a40ae276a7
- Local pid:
-
pubs:827881
- Source identifiers:
-
827881
- Deposit date:
-
2018-08-09
- ARK identifier:
Terms of use
- Copyright holder:
- Kalla et al
- Copyright date:
- 2014
- Notes:
- Copyright © 2014 The Authors. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record