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Superiority of a novel Mp1p antigen detection enzyme immunoassay compared to standard BACTEC blood culture in the diagnosis of talaromycosis

Abstract:

Background Talaromycosis is an invasive mycosis endemic in Southeast Asia and causes substantial morbidity and mortality in individuals with advanced HIV disease. Current diagnosis relies on isolating Talaromyces marneffei in cultures, which takes up to 14 days and is detectable only during late-stage infection, leading to high mortality.

Methods In this retrospective case-control study, we assessed the accuracy of a novel Mp1p antigen-detecting en...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/cid/ciaa826

Authors


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Name:
Wellcome Trust
Grant:
106680/Z/14/Z milestone CORE
Publisher:
Oxford University Press
Journal:
Clinical Infectious Diseases More from this journal
Volume:
73
Issue:
2
Pages:
e330-e336
Place of publication:
United States
Publication date:
2020-06-21
Acceptance date:
2020-06-16
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Pmid:
32564074
Language:
English
Keywords:
Pubs id:
1116256
Local pid:
pubs:1116256
Deposit date:
2020-07-06

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