Journal article icon

Journal article

Good laboratory practice: preventing introduction of bias at the bench.

Abstract:

BACKGROUND AND PURPOSE: As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review- Accumulating evidence suggests this may be due, at least in part, to problems in the design, conduct and reporting of animal experiments which create a systematic bias resulting in the overstatement of neuroprotective efficacy. CONCLUSIONS: Here, we set out a series of measu...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Journal:
Stroke; a journal of cerebral circulation More from this journal
Volume:
40
Issue:
3
Pages:
e50-e52
Publication date:
2009-03-01
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
Language:
English
Keywords:
Pubs id:
pubs:79184
UUID:
uuid:ab3a40ee-e371-4519-80e9-e613e60e40d2
Local pid:
pubs:79184
Source identifiers:
79184
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP