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T cell help mechanisms in the in vitro antibody response: the role of linked and non-linked recognition interactions.

Abstract:

Mechanisms by which T and B lymphocytes co-operate in the in vitro secondary antibody response to trinitrophenyl (TNP)-conjugated soluble protein antigens were investigated. The generation of antibody responses was analyzed when haptenic and carrier determinants were either linked or non-linked. Ability to co-operate through each of these mechanisms was influenced by the experimental conditions employed, particularly the mode of preparation of the T cells and the antigen concentration used. N...

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Publication status:
Published

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Authors


Sullivan, CP More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Immunology
Volume:
51
Issue:
2
Pages:
343-350
Publication date:
1984-02-05
EISSN:
1365-2567
ISSN:
0019-2805
URN:
uuid:ab04a246-5595-469d-88b9-00170e4bede9
Source identifiers:
7171
Local pid:
pubs:7171

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