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Journal article

Development and evaluation of an oligonucleotide ligation assay for detection of drug resistance-associated mutations in the human immunodeficiency virus type 2 pol gene.

Abstract:

Human immunodeficiency virus type 2 (HIV-2) is naturally resistant to several antiretroviral drugs, including all of the non-nucleoside reverse transcriptase inhibitors and the entry inhibitor T-20, and may have reduced susceptibility to some protease inhibitors. These resistance properties make treatment of HIV-2 patients difficult, with very limited treatment options. Therefore, early detection of resistance mutations is important for understanding treatment failures and guiding subsequent ...

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Publication status:
Published

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Publisher copy:
10.1128/jcm.02220-06

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Journal:
Journal of clinical microbiology
Volume:
45
Issue:
5
Pages:
1565-1571
Publication date:
2007-05-05
DOI:
EISSN:
1098-660X
ISSN:
0095-1137
URN:
uuid:aa7e3c87-1cdb-44a5-8a7f-bb7317650cb3
Source identifiers:
176610
Local pid:
pubs:176610

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