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Thesis

Investigating the role of scaffolds for rotator cuff repair

Abstract:

Surgical repairs of large-massive rotator cuff tendon tears often fail. Scaffolds can be used to augment tendon repair, but few scaffolds have demonstrated clinical efficacy. The aim of this thesis was to evaluate and compare several different types of commercially available scaffolds. Three important aspects of scaffold performance were studied: mechanical properties, tenocyte response, and macrophage response.

In terms of mechanical properties, synthetic scaffolds had super...

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Richard Smith More by this author

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Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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