Biological inferences from a mathematical model for malignant invasion.

Journal article

Invasive cells show changes in adhesion, motility and the protease-antiprotease balance. In this paper the authors derive a model based on a continuum approach that describes the behaviour of the invasive cells. The invasive cells are studied in the context of their interaction with normal cells, noninvasive tumour cells, ECM proteins and the proteases. The authors briefly describe the methods of mathematical analysis used and then go on to highlight the biological inferences drawn from the m...

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Authors: Perumpanani, A; Sherratt, J; Norbury, J; Byrne, H

• Publication status: Published
• Journal: Invasion and metastasis
• Volume: 16
• Issue: 4-5
• Pages: 209-221
• Publication date: 1996-01-01
• ISSN: 0251-1789
• Language: English
• Keywords: Animals; Phenotype; Neoplasm Invasiveness; Models, Biological; Humans; Mathematical Computing; Neoplasms