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Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.

Abstract:

Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously identified human leukocyte antigen (HLA) gene variants. To identify additional FL susceptibility loci, we conducted a large-scale two-stage GWAS in 4,523 case subjects and 13,344 control subjects of European ancestry. Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10(-20)) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10(-11)) near ETS1; 3q28 (rs6444305, p = 1.10 × 10(-10)) in LPP;...

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Publication status:
Published

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Publisher copy:
10.1016/j.ajhg.2014.09.004

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Publisher:
Cell Press
Journal:
American journal of human genetics
Volume:
95
Issue:
4
Pages:
462-471
Publication date:
2014-10-01
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
Source identifiers:
485994
Language:
English
Keywords:
Pubs id:
pubs:485994
UUID:
uuid:aa072f96-c2f4-4349-9c52-9d11a2d52474
Local pid:
pubs:485994
Deposit date:
2014-10-23

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