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Current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic review

Abstract:
This study aims to review the methodology and reporting of sample size calculation in a contemporary sample of hip and knee osteoarthritis trials. The choice of sample size is a key aspect of designing a clinical trial, ensuring that the trial is powered to detect clinically important treatment effects, is ethically sound and does not overuse resources. Accurate and complete reporting of the sample size calculation allows the reader to interpret the trial results alongside the aims and assumptions made when the trial was designed.
Publication status:
Published
Peer review status:
Reviewed (other)

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Publisher copy:
10.1016/j.joca.2018.02.555

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Centre for Statistics in Medicine
Oxford college:
Wolfson College
Role:
Author
ORCID:
0000-0001-9783-6549
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Role:
Author
ORCID:
0000-0003-0313-4429
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Oxford college:
St John's College
Role:
Author
ORCID:
0000-0003-4573-5257
Expand authors...
Publisher:
Elsevier Publisher's website
Journal:
OARSI World Congress on Osteoarthritis 2018 Journal website
Volume:
26
Issue:
S1
Pages:
S273-S274
Host title:
Osteoarthritis and Cartilage
Publication date:
2018-04-01
Acceptance date:
2018-01-08
Event location:
Liverpool, UK
Event start date:
2018-04-26T00:00:00Z
Event end date:
2018-04-29T00:00:00Z
DOI:
Source identifiers:
854648
Subtype:
Abstract
Pubs id:
pubs:854648
UUID:
uuid:aa04b914-403d-46df-afd1-21ffa88b2bdc
Local pid:
pubs:854648
Deposit date:
2018-07-09

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