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New genes in inflammatory bowel disease: lessons for complex diseases?

Abstract:

The chronic inflammatory bowel diseases Crohn's disease and ulcerative colitis are common causes of gastrointestinal disease in northern Europe, affecting as many as one in 250 people. Although mortality is low, morbidity associated with these diseases is substantial. We review the recent advances in the genetics of inflammatory bowel disease, with particular emphasis on the data that have been generated since the discovery of the CARD15 (NOD2) gene in 2001.

Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Oxford college:
Green Templeton College
Role:
Author
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Name:
Wellcome Trust
Grant:
072789/Z/03/Z
Publisher:
Elsevier
Journal:
Lancet More from this journal
Volume:
367
Issue:
9518
Pages:
1271-1284
Publication date:
2006-03-20
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
Pmid:
16631883
Language:
English
Keywords:
Pubs id:
pubs:827897
UUID:
uuid:aa02f388-9148-4847-9080-38bfc6c08154
Local pid:
pubs:827897
Source identifiers:
827897
Deposit date:
2018-08-09

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