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Skin mini-erosion technique for monitoring metabolites in interstitial fluid: its feasibility demonstrated by OGTT results in diabetic and non-diabetic subjects.

Abstract:

The aim of this study was to evaluate a new interstitial fluid (IF) sampling technique and its application in diabetology. IF and venous whole blood were sampled serially during an oral glucose tolerance test (OGTT) on days 1 and 3 after formation of a mini-erosion in eight non-diabetic controls and eight Type 2 diabetic subjects. Glucose, lactate, glycerol, 3-hydroxybutyrate and insulin were assayed in IF and plasma. With solitary exceptions, the IF sample volumes were in excess of those req...

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Publication status:
Published

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Publisher copy:
10.1080/00365519950185841

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Scandinavian journal of clinical and laboratory investigation More from this journal
Volume:
59
Issue:
2
Pages:
115-123
Publication date:
1999-04-01
DOI:
EISSN:
1502-7686
ISSN:
0036-5513
Language:
English
Keywords:
Pubs id:
pubs:25388
UUID:
uuid:a9eefdcd-b83c-4adb-ab1c-d3eb0150e7ce
Local pid:
pubs:25388
Source identifiers:
25388
Deposit date:
2012-12-19

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