Ventilatory acclimatization in response to very small changes in PO2 in humans.

Journal article

Ventilatory acclimatization to hypoxia (VAH) consists of a progressive increase in ventilation and decrease in end-tidal Pco(2) (Pet(CO(2))). Underlying VAH, there are also increases in the acute ventilatory sensitivities to hypoxia and hypercapnia. To investigate whether these changes could be induced with very mild alterations in end-tidal Po(2) (Pet(O(2))), two 5-day exposures were compared: 1) mild hypoxia, with Pet(O(2)) held at 10 Torr below the subject's normal value; and 2) mild hyper...

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Authors: Donoghue, S; Fatemian, M; Balanos, G; Crosby, A; Liu, C

• Publication status: Published
• Journal: Journal of applied physiology (Bethesda, Md. : 1985)
• Volume: 98
• Issue: 5
• Pages: 1587-1591
• Publication date: 2005-05-01
• DOI: 10.1152/japplphysiol.01019.2004
• EISSN: 1522-1601
• ISSN: 8750-7587
• Language: English
• Keywords: Blood Gas Analysis; Pulmonary Ventilation; Oxygen Consumption; Acclimatization; Carbon Dioxide; Female; Adult; Male; Oxygen; Humans