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Towards new copper based radiopharmaceuticals.

Abstract:

This paper reviews the research in progress in Oxford on the chemical, spectroscopic and redox properties of bis(thiosemicarbazonato) complexes of zinc and copper in the context of the hypoxia selectivity of the copper(II) complex. Also, covered are synthetic strategies for modified complexes with a range of functional substituents and the in vitro and in vivo characteristics of two of these derivatives are described. Finally, the synthesis of some new bifunctional macrocyclic ligands is desc...

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Publication status:
Published

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Journal:
quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.. More from this journal
Volume:
52
Issue:
2
Pages:
174-184
Publication date:
2008-06-01
EISSN:
1827-1936
ISSN:
1824-4785
Language:
English
Keywords:
Pubs id:
pubs:323826
UUID:
uuid:a9c77a59-126c-4a82-ad6b-4e7ccd64e556
Local pid:
pubs:323826
Source identifiers:
323826
Deposit date:
2012-12-19

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