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Localization of interferons and interleukin 2 in polymyositis and muscular dystrophy.

Abstract:

Muscle biopsies from nine patients with polymyositis, six with muscular dystrophy, six with other muscle diseases and three controls have been studied with a panel of 10 monoclonal antibodies (MoAb) identifying T lymphocytes, HLA-class I antigens, alpha, beta and gamma interferons and interleukin 2 (IL-2). The result confirm that the staining of the sarcolemma with anti-HLA class I antibody is weak or negative, except in areas adjacent to infiltrating leucocytes or where muscle fibre damage i...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
Clinical and experimental immunology
Volume:
63
Issue:
2
Pages:
450-458
Publication date:
1986-02-05
EISSN:
1365-2249
ISSN:
0009-9104
URN:
uuid:a9c04dc2-a89b-4971-82f8-2079ace4b05f
Source identifiers:
35152
Local pid:
pubs:35152

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