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Journal article

Rare Nav1.7 variants associated with painful diabetic peripheral neuropathy

Abstract:

Diabetic peripheral neuropathy (DPN) is a common disabling complication of diabetes. Almost half of DPN patients develop neuropathic pain for which current analgesic treatments are inadequate. Understanding the role of genetic variability in the development of painful DPN is needed for improved understanding of pain pathogenesis, for better patient stratification in clinical trials and to target therapy more appropriately. Here we examined the relationship between variants in the voltage gate...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1097/j.pain.0000000000001116

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy & Genetics
Role:
Author
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Novo Nordisk Foundation More from this funder
Publisher:
Lippincott, Williams and Wilkins Publisher's website
Journal:
PAIN Journal website
Volume:
159
Issue:
3
Pages:
469–480
Publication date:
2017-11-05
Acceptance date:
2017-10-11
DOI:
EISSN:
1872-6623
ISSN:
0304-3959
Pubs id:
pubs:735200
URN:
uri:a9b3c106-af03-4703-b298-40ed027dd611
UUID:
uuid:a9b3c106-af03-4703-b298-40ed027dd611
Local pid:
pubs:735200

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