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Journal article

Post-marketing withdrawal of anti-obesity medicinal products because of adverse drug reactions: a systematic review.

Abstract:

Background

We identified anti-obesity medications withdrawn since 1950 because of adverse drug reactions after regulatory approval, and examined the evidence used to support such withdrawals, investigated the mechanisms of the adverse reactions, and explored the trends over time.

Methods

We conducted searches in PubMed, the World Health Organization database of drugs, the websites of drug regulatory authorities, and selected full texts, and we hand searched refere...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/s12916-016-0735-y

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Societies, Other & Subsidiary Companies
Department:
Kellogg College
Oxford college:
Kellogg College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
More from this funder
Funding agency for:
Onakpoya, I
Grant:
Clarendon Fund
Publisher:
BioMed Central Publisher's website
Journal:
BioMed Central Medicine Journal website
Volume:
14
Issue:
1
Pages:
191
Publication date:
2016-11-01
Acceptance date:
2016-10-27
DOI:
ISSN:
1741-7015
Language:
English
Keywords:
Pubs id:
pubs:664392
UUID:
uuid:a9a62c84-0ae7-4a40-a15e-f9d53ad03bf4
Local pid:
pubs:664392
Source identifiers:
664392
Deposit date:
2017-03-08

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