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Evaluation of safety of preoperative GLP-1 receptor agonists in patients undergoing elective surgery: a systematic review, meta-analysis and meta-regression

Abstract:

BackgroundObesity remains a major global public health challenge, particularly among surgical patients, where it can be associated with increased perioperative and longer-term risk. While preoperative weight management strategies are often used to mitigate these risks, scalable interventions remain limited. Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are an emerging pharmacological approach for weight loss, but their perioperative safety remains uncertain. This study aimed to assess ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.eclinm.2025.103408

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Institution:
University of Oxford
Role:
Author


Publisher:
Elsevier
Journal:
EClinicalMedicine More from this journal
Volume:
87
Pages:
103408
Publication date:
2025-08-12
Acceptance date:
2025-07-22
DOI:
EISSN:
2589-5370
ISSN:
2589-5370
Pmid:
41054439


Language:
English
Keywords:
Pubs id:
2286489
Local pid:
pubs:2286489
Source identifiers:
3372228
Deposit date:
2025-10-15
ARK identifier:
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