Journal article : Review

Non-invasive investigation of myocardial energetics in cardiac disease using 31P magnetic resonance spectroscopy

Abstract:: Cardiac metabolism and function are intrinsically linked. High-energy phosphates occupy a central and obligate position in cardiac metabolism, coupling oxygen and substrate fuel delivery to the myocardium with external work. This insight underlies the widespread clinical use of ischaemia testing. However, other deficits in high-energy phosphate metabolism (not secondary to supply-demand mismatch of oxygen and substrate fuels) may also be documented, and are of particular interest when found in the context of structural heart disease. This review introduces the scope of deficits in high-energy phosphate metabolism that may be observed in the myocardium, how to assess for them, and how they might be interpreted.

Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Peterzan, M. A., Lewis, A. J. M., Neubauer, S., & Rider, O. J. (2020). Non-invasive investigation of myocardial energetics in cardiac disease using 31P magnetic resonance spectroscopy. Cardiovascular Diagnosis and Therapy, 10(3), 625–635.

MLA Style

Peterzan, M. A., et al. “Non-Invasive Investigation of Myocardial Energetics in Cardiac Disease Using 31P Magnetic Resonance Spectroscopy.” Cardiovascular Diagnosis and Therapy, vol. 10, no. 3, AME Publishing Company, 2020, pp. 625–35.

Chicago Style

Peterzan, MA, AJM Lewis, S Neubauer, and OJ Rider. 2020. “Non-Invasive Investigation of Myocardial Energetics in Cardiac Disease Using 31P Magnetic Resonance Spectroscopy.” Cardiovascular Diagnosis and Therapy 10 (3): 625–35.
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Files:: 45454-PB4-6580-R3.pdf

(Preview, Version of record, 384.7KB, Terms of use)

Publisher copy:: 10.21037/cdt-20-275

Authors

+ Peterzan, MA More by this author

Role:: Author

+ Lewis, AJM More by this author

Role:: Author

+ Neubauer, S More by this author

Role:: Author

+ Rider, OJ More by this author

Institution:: University of Oxford
Division:: MSD
Department:: RDM
Sub department:: RDM Cardiovascular Medicine
Role:: Author

Publisher:: AME Publishing Company
Journal:: Cardiovascular Diagnosis and Therapy More from this journal
Volume:: 10
Issue:: 3
Pages:: 625-635
Publication date:: 2020-06-01
Acceptance date:: 2020-05-07
DOI:: 10.21037/cdt-20-275
EISSN:: 2223-3660
ISSN:: 2223-3652
Pmid:: 32695642

Language:: English
Keywords:: energetics

cardiac magnetic resonance (CMR)

magnetic resonance spectroscopy

FFR
Subtype:: Review
Pubs id:: 1121167
Local pid:: pubs:1121167
Deposit date:: 2020-08-13

Terms of use

Copyright holder:: Peterzan et al.
Copyright date:: 2020
Rights statement:: Copyright © 2020 The Author(s). This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

Licence:: CC Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND)

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