- Abstract:
-
In Plasmodium falciparum-endemic areas, pregnancy-associated malaria (PAM) is an important health problem. The condition is precipitated by accumulation of parasite-infected erythrocytes (IEs) in the placenta, and this process is mediated by parasite-encoded variant surface antigens (VSA) binding to chondroitin sulfate A (CSA). Parasites causing PAM express unique VSA types, VSAPAM, which can be serologically classified as sex specific and parity dependent. It is sex specific because men from...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1084/jem.20041579
-
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- Journal:
- The Journal of experimental medicine
- Volume:
- 200
- Issue:
- 9
- Pages:
- 1197-1203
- Publication date:
- 2004-11-05
- DOI:
- EISSN:
-
1540-9538
- ISSN:
-
0022-1007
- URN:
-
uuid:a9259040-7b84-4df3-82f7-730037fa2a7e
- Source identifiers:
-
140123
- Local pid:
- pubs:140123
- Copyright date:
- 2004
Journal article
Evidence for the involvement of VAR2CSA in pregnancy-associated malaria.
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