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Journal article

Evidence for the involvement of VAR2CSA in pregnancy-associated malaria.

Abstract:

In Plasmodium falciparum-endemic areas, pregnancy-associated malaria (PAM) is an important health problem. The condition is precipitated by accumulation of parasite-infected erythrocytes (IEs) in the placenta, and this process is mediated by parasite-encoded variant surface antigens (VSA) binding to chondroitin sulfate A (CSA). Parasites causing PAM express unique VSA types, VSAPAM, which can be serologically classified as sex specific and parity dependent. It is sex specific because men from...

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Publication status:
Published

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Publisher copy:
10.1084/jem.20041579

Authors


Salanti, A More by this author
Dahlbäck, M More by this author
Nielsen, MA More by this author
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Journal:
The Journal of experimental medicine
Volume:
200
Issue:
9
Pages:
1197-1203
Publication date:
2004-11-05
DOI:
EISSN:
1540-9538
ISSN:
0022-1007
URN:
uuid:a9259040-7b84-4df3-82f7-730037fa2a7e
Source identifiers:
140123
Local pid:
pubs:140123

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