Repeated colonoscopic screening of patients with acromegaly: 15-year experience identifies those at risk of new colonic neoplasia and allows for effective screening guidelines.

Journal article

OBJECTIVE: It is suggested that patients with acromegaly have an increased risk of colorectal cancer and pre-malignant adenomatous polyps. However, the optimum frequency with which colonoscopic screening should be offered remains unclear. DESIGN: To determine the optimum frequency for repeated colonoscopic surveillance of acromegalic patients. METHODS: We retrospectively reviewed the case records of all patients with acromegaly seen in our centre since 1992: 254 patients had at least one sur...

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Authors: Dworakowska, D; Gueorguiev, M; Kelly, P; Monson, J; Besser, G

• Publication status: Published
• Journal: European journal of endocrinology / European Federation of Endocrine Societies
• Volume: 163
• Issue: 1
• Pages: 21-28
• Publication date: 2010-07-01
• DOI: 10.1530/eje-09-1080
• EISSN: 1479-683X
• ISSN: 0804-4643
• Language: English
• Keywords: Middle Aged; Human Growth Hormone; Male; Radioimmunoassay; Aged; Colonic Neoplasms; Acromegaly; Colonoscopy; Adenomatous Polyps; Colon; Humans; Insulin-Like Growth Factor I