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Journal article

Inference, validation, and dynamic modeling of transcription networks in multipotent hematopoietic cells.

Abstract:

Identifying the transcription factor interactions that are responsible for cell-specific gene expression programs is key to understanding the regulation of cell behaviors, such as self-renewal, proliferation, differentiation, and death. The rapidly increasing availability of microarray-derived global gene expression data sets, coupled with genome sequence information from multiple species, has driven the development of computational methods to reverse engineer and dynamically model genetic re...

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Publication status:
Published

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Publisher copy:
10.1196/annals.1392.018

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
Role:
Author
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Journal:
Annals of the New York Academy of Sciences
Volume:
1106
Issue:
1
Pages:
30-40
Publication date:
2007-06-05
DOI:
EISSN:
1749-6632
ISSN:
0077-8923
URN:
uuid:a918fe44-9399-4ca0-b907-a0935518c421
Source identifiers:
106152
Local pid:
pubs:106152

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