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A solute gradient in the tear meniscus II. implications for lid margin disease, including meibomian gland dysfunction

Abstract:

We have hypothesized previously that evaporation from the tears generates a solute gradient across the tear meniscus, which delivers hyperosmolar stress to the mucocutaneous junction (MCJ) of the lid margin. This is proposed as the basis for Marx's line, a line of staining with topically applied dyes that lies directly behind the MCJ. In this article, we consider the implications of this hypothesis for progressive damage to the lid margin as an age-related phenomenon, its amplification in dry...

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Publication date:
2011-01-01
UUID:
uuid:a90af212-5764-4d9d-b9f4-a615bec3a631
Local pid:
oai:eprints.maths.ox.ac.uk:1504
Deposit date:
2012-03-31

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