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Journal article

Molecular subgroup of primary prostate cancer presenting with metastatic biology.

Abstract:

Background

Approximately 4–25% of patients with early prostate cancer develop disease recurrence following radical prostatectomy.

Objective

To identify a molecular subgroup of prostate cancers with metastatic potential at presentation resulting in a high risk of recurrence following radical prostatectomy.

Design, setting, and participants

Unsupervised hierarchical clustering was performed using gene expression data from 70 primary resections, 31 me...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1016/j.eururo.2017.03.027

Authors


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Belfast-Manchester Movember Centre of Excellence More from this funder
Almac Diagnostics More from this funder
European Regional Development Fund More from this funder
Prostate Cancer UK More from this funder
Publisher:
Elsevier Publisher's website
Journal:
European Urology Journal website
Volume:
72
Issue:
4
Pages:
509-518
Publication date:
2017-04-01
Acceptance date:
2017-03-17
DOI:
EISSN:
1873-7560
ISSN:
0302-2838
Pmid:
28408174
Source identifiers:
690266
Language:
English
Keywords:
Pubs id:
pubs:690266
UUID:
uuid:a8ffec4f-3e79-4de9-b9c7-0b9ae3c89351
Local pid:
pubs:690266
Deposit date:
2018-01-11

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