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Imaging single glycans

Abstract:

Imaging of biomolecules guides our understanding of their diverse structures and functions1,2. Real-space imaging at sub-nanometre resolution using cryo-electron microscopy has provided key insights into proteins and their assemblies3,4. Direct molecular imaging of glycans—the predominant biopolymers on Earth, with a plethora of structural and biological functions5—has not been possible so far6. The inherent glycan complexity and backbone flexibility require single-molecule approaches for rea...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41586-020-2362-1

Authors


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Role:
Author
ORCID:
0000-0002-2252-322X
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Role:
Author
ORCID:
0000-0002-4580-9597
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Role:
Author
ORCID:
0000-0001-8598-8035
Publisher:
Springer Nature
Journal:
Nature More from this journal
Volume:
582
Issue:
7812
Pages:
375-378
Publication date:
2020-06-17
Acceptance date:
2020-03-27
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Pmid:
32555487
Language:
English
Keywords:
Pubs id:
1113683
Local pid:
pubs:1113683
Deposit date:
2020-08-25

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