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Finite element study of oxygen diffusion in the intervertebral disc

Abstract:

The intervertebral disc consists of a water-rich extra-cellular matrix which is synthesized and maintained by its cells. The disc is the largest avascular tissue in the body with its cells lying as much as 8mm away from the blood supply. Nutrients, essential for maintaining cellular viability, diffuse through the matrix from blood supply under a concentration gradient arising from cellular demand. The oxygen concentration gradients in the intervertebral disc are investigated to examine the ef...

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Authors


Sélard, E More by this author
Shirazi-Adl, A More by this author
Urban, JPG More by this author
Journal:
American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume:
48
Pages:
285-286
Publication date:
2000
ISSN:
1071-6947
URN:
uuid:a884d9ef-6da0-470f-ae2b-6fb5bc15ce7e
Source identifiers:
238306
Local pid:
pubs:238306
Language:
English

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