Journal article
High-speed fixed-target serial virus crystallography
- Abstract:
-
We report a method for serial X-ray crystallography at X-ray free-electron lasers (XFELs), which allows for full use of the current 120-Hz repetition rate of the Linear Coherent Light Source (LCLS). Using a micropatterned silicon chip in combination with the high-speed Roadrunner goniometer for sample delivery, we were able to determine the crystal structures of the picornavirus bovine enterovirus 2 (BEV2) and the cytoplasmic polyhedrosis virus type 18 polyhedrin, with total data collection t...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 680.4KB)
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- Publisher copy:
- 10.1038/nmeth.4335
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Authors
Funding
+ US National Institutes of Health
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Funding agency for:
Sauter, N
Grant:
GM117126
European Cluster of Advanced Laser Light Sources
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Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Nature Methods Journal website
- Volume:
- 14
- Issue:
- 8
- Pages:
- 805-810
- Publication date:
- 2017-06-19
- Acceptance date:
- 2017-05-15
- DOI:
- EISSN:
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1548-7105
- ISSN:
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1548-7091
- Pmid:
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28628129
- Source identifiers:
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702249
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:702249
- UUID:
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uuid:a86c02c0-c9a0-4567-93a9-e997c87a91b3
- Local pid:
- pubs:702249
- Deposit date:
- 2017-10-09
Terms of use
- Copyright holder:
- Roedig, et al 2017
- Copyright date:
- 2017
- Notes:
- This is the author accepted manuscript following peer review version of the article. The final version is available online from Nature Publishing Group at: 10.1038/nmeth.4335
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