The Collaborative Cross, a community resource for the genetic analysis of complex traits.

Journal article

The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specific...

Expand abstract

Authors: Churchill, G; Airey, D; Allayee, H; Angel, J; Attie, A

• Publication status: Published
• Journal: Nature genetics
• Volume: 36
• Issue: 11
• Pages: 1133-1137
• Publication date: 2004-11-01
• DOI: 10.1038/ng1104-1133
• EISSN: 1546-1718
• ISSN: 1061-4036
• Language: English
• Keywords: Community Networks; Animals; Breeding; Databases, Genetic; Complex Trait Consortium; Crosses, Genetic; Humans; Recombination, Genetic; Mice, Inbred Strains; Mice; Health Services Research; Health Resources