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Quantification and significance of fluid shear stress field in biaxial cell stretching device

Abstract:

A widely used commercially available system for the investigation of mechanosensitivity applies a biaxial strain field to cells cultured on a compliant silicone substrate membrane stretched over a central post. As well as intended substrate strain, this device also provides a fluid flow environment for the cultured cells. In order to interpret the relevance of experiments using this device to the in vivo and clinical situation, it is essential to characterise both substrate and fluid environm...

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Publisher copy:
10.1007/s10237-010-0255-1

Authors


Thompson, MS More by this author
Abercrombie, SR More by this author
Bieler, FH More by this author
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Journal:
Biomechanics and Modeling in Mechanobiology
Volume:
10
Issue:
4
Pages:
559-564
Publication date:
2011-07-05
DOI:
EISSN:
1682-2978
ISSN:
1617-7959
URN:
uuid:a816053a-2d5d-46ed-84c2-9e027431eb58
Source identifiers:
193007
Local pid:
pubs:193007

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