Journal article icon

Journal article

Assessment of immune interference, antagonism, and diversion following human immunization with biallelic blood-stage malaria viral-vectored vaccines and controlled malaria infection.

Abstract:

Overcoming antigenic variation is one of the major challenges in the development of an effective vaccine against Plasmodium falciparum, a causative agent of human malaria. Inclusion of multiple Ag variants in subunit vaccine candidates is one strategy that has aimed to overcome this problem for the leading blood-stage malaria vaccine targets, that is, merozoite surface protein 1 (MSP1) and apical membrane Ag 1 (AMA1). However, previous studies, utilizing malaria Ags, have concluded that inclu...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.4049/jimmunol.1201455

Authors


Collins, KA More by this author
Halstead, FD More by this author
Choudhary, P More by this author
Expand authors...
Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
190
Issue:
3
Pages:
1135-1147
Publication date:
2013-02-05
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:a7f096ef-d0a7-4d98-a910-99d0ad8f71b1
Source identifiers:
374230
Local pid:
pubs:374230

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP