Journal article
A time-course comparative clinical and immune response evaluation study between the human pathogenic Orientia tsutsugamushi strains: Karp and Gilliam in a rhesus macaque (Macaca mulatta) model
- Abstract:
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Background
Expand abstract
Scrub typhus is a vector-borne febrile illness caused by Orientia tsutsugamushi transmitted by the bite of Trombiculid mites. O. tsutsugamushi has a high genetic diversity and is increasingly recognized to have a wider global distribution than previously assumed.
Methodology/principle findings
We evaluated the clinical outcomes and host immune responses of the two most relevant human pathogenic strains of O. tsutsug...
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 3.3MB, Terms of use)
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(Preview, Corrected version of record, pdf, 229.3KB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pntd.0010611
Authors
- Publisher:
- Public Library of Science
- Journal:
- PLoS Neglected Tropical Diseases More from this journal
- Volume:
- 16
- Issue:
- 8
- Article number:
- e0010611
- Publication date:
- 2022-08-04
- Acceptance date:
- 2022-06-27
- DOI:
- EISSN:
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1935-2735
- ISSN:
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1935-2727
- Pmid:
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35925895
- Language:
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English
- Keywords:
- Pubs id:
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1272607
- Local pid:
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pubs:1272607
- Deposit date:
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2022-11-08
Terms of use
- Copyright holder:
- Inthawong et al.
- Copyright date:
- 2022
- Rights statement:
- This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.
- Notes:
- A correction to this article is available online from Public Library of Science at: https://doi.org/10.1371/journal.pntd.0011277
- Licence:
- CC Public Domain Dedication (CC0)
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