- Abstract:
-
Genome-wide association studies (GWAS) have identified >500 common variants associated with quantitative metabolic traits, but in aggregate such variants explain at most 20-30% of the heritable component of population variation in these traits. To further investigate the impact of genotypic variation on metabolic traits, we conducted re-sequencing studies in >6,000 members of a Finnish population cohort (The Northern Finland Birth Cohort of 1966 [NFBC]) and a type 2 diabetes case-contro...
Expand abstract - Publisher copy:
- 10.1371/journal.pgen.1004147
-
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- Journal:
- PLoS Genetics
- Volume:
- 10
- Issue:
- 1
- Publication date:
- 2014-01-05
- DOI:
- EISSN:
-
1553-7404
- ISSN:
-
1553-7390
- URN:
-
uuid:a7ba6727-91dc-4ba8-a3bb-bb29b674e898
- Source identifiers:
-
459206
- Local pid:
- pubs:459206
- Language:
- English
- Copyright date:
- 2014
Journal article
Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci
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