- Abstract:
-
Base excision repair (BER) is a frontline repair system that is responsible for maintaining genome integrity and thus preventing premature aging, cancer and many other human diseases by repairing thousands of DNA lesions and strand breaks continuously caused by endogenous and exogenous mutagens. This fundamental and essential function of BER not only necessitates tight control of the continuous availability of basic components for fast and accurate repair, but also requires temporal and spati...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.8MB)
-
- Publisher copy:
- 10.1093/nar/gkt076
-
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- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Nucleic acids research Journal website
- Volume:
- 41
- Issue:
- 6
- Pages:
- 3483-3490
- Publication date:
- 2013-04-05
- DOI:
- EISSN:
-
1362-4962
- ISSN:
-
0305-1048
- URN:
-
uuid:a7b9aa9d-e409-4da9-87fe-671cbb31b182
- Source identifiers:
-
384174
- Local pid:
- pubs:384174
- Copyright holder:
- Grigory L. Dianov1 and Ulrich Hübscher
- Copyright date:
- 2013
- Notes:
- Copyright © 2013 Grigory L. Dianov and Ulrich Hübscher. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Mammalian base excision repair: the forgotten archangel.
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Swiss National Science Foundation
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