The detection of cytomegalovirus DNA in maternal plasma is associated with mortality in HIV-1-infected women and their infants.

Journal article

OBJECTIVE: Cytomegalovirus (CMV) is an important pathogen in healthy neonates and individuals with human immunodeficiency virus (HIV-1). The objective of this study was to determine whether the detection of CMV DNA (CMV DNAemia) in maternal plasma was associated with mortality in HIV-1-infected women or their infants. METHODS: A longitudinal study was designed to examine the relationship between maternal CMV DNAemia and maternal-infant mortality during 2 years postpartum. Sixty-four HIV-1-inf...

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Authors: Slyker, J; Lohman-Payne, B; Rowland-Jones, S; Otieno, P; Maleche-Obimbo, E

• Publication status: Published
• Journal: AIDS (London, England)
• Volume: 23
• Issue: 1
• Pages: 117-124
• Publication date: 2009-01-01
• DOI: 10.1097/qad.0b013e32831c8abd
• EISSN: 1473-5571
• ISSN: 0269-9370
• Language: English
• Keywords: Viral Load; Cytomegalovirus Infections; Viremia; Cytomegalovirus; Female; CD4 Lymphocyte Count; AIDS-Related Opportunistic Infections; Adult; Prognosis; HIV-1; Infectious Disease Transmission, Vertical; Disease Progression; Young Adult; DNA, Viral; Epidemiologic Methods; Infant, Newborn; Pregnancy Complications, Infectious; Pregnancy; Humans