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Dipeptidyl peptidase IV inhibitors as novel regulators of vascular disease

Abstract:

Dipeptidyl peptidase IV (DPP-IV) has been revealed as an adipokine with potential relevance in cardiovascular disease (CVD), while clinically used DPP-IV inhibitors have demonstrated beneficial cardiovascular effects in several experimental studies. Perivascular adipose tissue (PVAT) is a unique adipose tissue depot in close anatomical proximity and bidirectional functional interaction with the vascular wall, which is a source of DPP-IV and its biology may be influenced by DPP-IV inhibition. ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.vph.2017.07.001

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Institution:
University of Oxford
Oxford college:
Trinity College
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
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Funding agency for:
Antoniades, C
Grant:
NNF15CC0018486
More from this funder
Funding agency for:
Antoniades, C
Grant:
NNF15CC0018486
More from this funder
Funding agency for:
Antoniades, C
Grant:
NNF15CC0018486
Publisher:
Elsevier Publisher's website
Journal:
Vascular Pharmacology Journal website
Volume:
96-98
Pages:
1-4
Publication date:
2017-07-08
Acceptance date:
2017-07-01
DOI:
EISSN:
1879-3649
ISSN:
1537-1891
Source identifiers:
708117
Language:
English
Keywords:
Pubs id:
pubs:708117
UUID:
uuid:a6b83ba7-b817-4476-a5d7-6c4652cd8c2e
Local pid:
pubs:708117
Deposit date:
2017-07-21

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