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Forecasting paediatric malaria admissions on the Kenya Coast using rainfall

Abstract:
Background Malaria is a vector-borne disease which, despite recent scaled-up efforts to achieve control in Africa, continues to pose a major threat to child survival. The disease is caused by the protozoan parasite Plasmodium and requires mosquitoes and humans for transmission. Rainfall is a major factor in seasonal and secular patterns of malaria transmission along the East African coast. Objective The goal of the study was to develop a model to reliably forecast incidences of paediatric malaria admissions to Kilifi District Hospital (KDH). Design In this article, we apply several statistical models to look at the temporal association between monthly paediatric malaria hospital admissions, rainfall, and Indian Ocean sea surface temperatures. Trend and seasonally adjusted, marginal and multivariate, time-series models for hospital admissions were applied to a unique data set to examine the role of climate, seasonality, and long-term anomalies in predicting malaria hospital admission rates and whether these might become more or less predictable with increasing vector control. Results The proportion of paediatric admissions to KDH that have malaria as a cause of admission can be forecast by a model which depends on the proportion of malaria admissions in the previous 2 months. This model is improved by incorporating either the previous month's Indian Ocean Dipole information or the previous 2 months’ rainfall. Conclusions Surveillance data can help build time-series prediction models which can be used to anticipate seasonal variations in clinical burdens of malaria in stable transmission areas and aid the timing of malaria vector control.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3402/gha.v9.29876

Authors

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Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0003-3725-6088


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Grant:
103602/Z/14/Z
103602/Z/14/Z


Publisher:
Taylor & Francis Open
Journal:
Global Health Action More from this journal
Volume:
9
Issue:
1
Article number:
29876
Place of publication:
United States
Publication date:
2016-02-02
Acceptance date:
2015-12-29
DOI:
EISSN:
1654-9880
ISSN:
1654-9716
Pmid:
26842613


Language:
English
Keywords:
Pubs id:
601494
Local pid:
pubs:601494
Deposit date:
2020-03-30
ARK identifier:

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