Journal article
Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth.
- Abstract:
-
Antibodies that neutralize (nAbs) genetically diverse HIV-1 strains have been recovered from a subset of HIV-1 infected subjects during chronic infection. Exact mechanisms that expand the otherwise narrow neutralization capacity observed during early infection are, however, currently undefined. Here we characterized the earliest nAb responses in a subtype A HIV-1 infected Rwandan seroconverter who later developed moderate cross-clade nAb breadth, using (i) envelope (Env) glycoproteins from th...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Pathog Journal website
- Volume:
- 9
- Issue:
- 2
- Article number:
- e1003173
- Publication date:
- 2013-02-01
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
- Source identifiers:
-
387767
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:387767
- UUID:
-
uuid:a632f1b3-f247-47eb-ab0a-4eb5b2ac0f1b
- Local pid:
- pubs:387767
- Deposit date:
- 2013-11-16
Terms of use
- Copyright holder:
- Murphy et al
- Copyright date:
- 2013
- Notes:
- © 2013 Murphy et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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