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Improved clinical outcome measures of knee pain and function with concurrent resolution of subchondral Bone Marrow Edema Lesion and joint effusion in an osteoarthritic patient following Pentosan Polysulphate Sodium treatment: a case report

Abstract:

Background

At present, there are no registered products for the treatment of subchondral Bone Marrow Edema Lesion (BML) and associated knee pain. Patients who do not respond to current anti-inflammatory therapies are left with limited treatment options, and may resort to operative management with Total Knee Arthroplasty (TKA). We report the use of Pentosan Polysulphate Sodium (PPS) for the treatment of BMLs of the knee.

Case presentation

We report the case of a 70...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12891-017-1754-3

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0002-8942-2167
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Publisher:
BioMed Central Publisher's website
Journal:
BMC Musculoskeletal Disorders Journal website
Volume:
18
Issue:
1
Pages:
396
Publication date:
2017-09-12
Acceptance date:
2017-09-05
DOI:
EISSN:
1471-2474
ISSN:
1471-2474
Pubs id:
pubs:935103
URN:
uri:a6150a0a-fb8b-49c2-9c29-e75e4d0af747
UUID:
uuid:a6150a0a-fb8b-49c2-9c29-e75e4d0af747
Local pid:
pubs:935103

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