- Abstract:
-
Lysine methylation of histones is recognized as an important component of an epigenetic indexing system demarcating transcriptionally active and inactive chromatin domains. Trimethylation of histone H3 lysine 4 (H3K4me3) marks transcription start sites of virtually all active genes. Recently, we reported that the WD40-repeat protein WDR5 is important for global levels of H3K4me3 and control of HOX gene expression. Here we show that a plant homeodomain (PHD) finger of nucleosome remodelling fa...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/nature04815
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- Journal:
- Nature
- Volume:
- 442
- Issue:
- 7098
- Pages:
- 86-90
- Publication date:
- 2006-07-05
- DOI:
- EISSN:
-
1476-4687
- ISSN:
-
0028-0836
- URN:
-
uuid:a6080550-6947-4dde-bcdc-100ef5be70f5
- Source identifiers:
-
331915
- Local pid:
- pubs:331915
- Language:
- English
- Keywords:
- Copyright date:
- 2006
Journal article
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.
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