Journal article
Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis.
- Abstract:
-
The c-Jun N-terminal kinase (JNK) signaling pathway plays a critical role in mediating apoptosis in the nervous system; however, the mechanisms by which JNK triggers neuronal apoptosis remain incompletely understood. Recent studies suggest that in addition to inducing transcription of pro-apoptotic genes, JNK also directly activates the cell death machinery. Here, we report that JNK catalyzed the phosphorylation of the BH3-only protein Bcl-2 interacting mediator of cell death (BimEL) at serin...
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- Publication status:
- Published
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- Publisher copy:
- 10.1523/jneurosci.2953-04.2004
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Authors
Bibliographic Details
- Journal:
- Journal of neuroscience : the official journal of the Society for Neuroscience
- Volume:
- 24
- Issue:
- 40
- Pages:
- 8762-8770
- Publication date:
- 2004-10-01
- DOI:
- EISSN:
-
1529-2401
- ISSN:
-
0270-6474
- Source identifiers:
-
248015
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:248015
- UUID:
-
uuid:a530a4bd-c331-4c57-a1fe-27eabb218022
- Local pid:
- pubs:248015
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2004
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